Discovery, producing organism and structure (1,2)
Luminamicin was isolated from a culture broth of the actinomycete strain OMR-59. It exhibits antibacterial activity against anaerobic bacteria, particularly Clostridium sp. (1,2). Luminamicin is identical to coloradocin, discovered by Abbott’s group to be an anti-anaerobe antibiotic. The structure of coloradocin was elucidated by Rasmussen et al (3).
Colorless needles; C32H38O12; mol wt 614.24. Sol. in MeOH, acetone, EtOAc. Insol. in H2O, hexane.
Biological activity (1,2)
Antimicrobial activity (1,2).
1.  S. Ōmura et al., J. Antibiot., 38, 1322–1326 (1985)
2.  S. Taga et al., Kitasato Arch. Exp. Med., 60, 15–24 (1987)
3. R. Rasmussen et al., J. Antibiot., 40, 1383–1393 (1987).