Rokitamycin
Rokitamycin prepared from leucomycin A5 shows higher antibacterial activity in vitro and higher serum levels than leucomycins (1,2). Therefore, the derivative has been clinically used as an antibacterial agent.
References
1. [190] S. Ōmura et al., J. Med. Chem., 15, 1011-1015 (1972)
2. [213] H. Sakakibara et al., J. Antibiot., 34, 1001-1010 (1981)